Adrenocortical Hyperfunction in “Idiopathic” Hirsutism and the Stein-Leventhal Syndrome1

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The Stein-Leventhal syndrome; a curable form of sterility.

In 1958, Irving Freiler Stein Sr. published ?The Stein-Leventhal Syndrome: A Curable Form of Sterility? documenting his findings on the diagnosis and surgical treatment of Stein-Leventhal syndrome. Stein-Leventhal syndrome, later called polycystic ovarian syndrome (PCOS), affects the reproductive health of women. Common symptoms include excess body hair, a lack of menstrual cycle or amenorrhea,...

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Idiopathic hirsutism.

Hirsutism, the presence of terminal (coarse) hairs in females in a male-like pattern, affects between 5% and 10% of women. Of the sex steroids, androgens are the most important in determining the type and distribution of hairs over the human body. Under the influence of androgens hair follicles that are producing vellus-type hairs can be stimulated to begin producing terminal hairs (i.e., termi...

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Adrenocortical Hyperfunction and Oat-Cell Carcinoma of the Bronchus

The association of increased adrenocortical activity with carcinoma in certain site notably the bronchus, has been increasingly recognised in recent years (Allott; Skelton, i960; Bagshawe, i960). About fifty cases have been reported to date. It possible, however, that the association is not as rare as this figure would suggest, sin1; a number of these patients have not had the clinical features...

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Prevalence of idiopathic hirsutism.

OBJECTIVE To evaluate the prevalence of idiopathic hirsutism in a large population of hirsute women. DESIGN 588 hirsute women (mean age 24+/-1, range 15-36 years) were evaluated as outpatients at the Department of Endocrinology of the University of Palermo, Italy. The diagnosis of idiopathic hirsutism was established in hirsute patients presenting regular ovulatory menstrual cycles and normal...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1958

ISSN: 0021-9738

DOI: 10.1172/jci103666